Pharmacology Antiviral Agents Practice Test 2026 – Complete Exam Prep

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When prescribed zidovudine for HIV treatment, which statement indicates understanding of the medication's action?

"Zidovudine inactivates the virus and prevents recurrence of the disease."

"Zidovudine slows the progression of the disease but does not cure it."

Zidovudine, also known as AZT, is an antiretroviral medication used primarily in the treatment of HIV. It functions as a nucleoside reverse transcriptase inhibitor (NRTI), which means it works by interfering with the virus's ability to replicate its genetic material. The selected statement accurately reflects the role of zidovudine in managing HIV infection. While zidovudine effectively reduces the viral load in the body and helps preserve immune function, it does not eliminate the virus; hence, it slows the progression of HIV disease but does not cure the infection.

The understanding that zidovudine slows disease progression aligns with what is known regarding HIV treatment. By lowering the viral load, the medication allows for a healthier immune system and reduces the risk of developing AIDS and related complications, but it does not eradicate the virus from the body.

While it is true that zidovudine can lead to the development of resistant strains of the virus and that it may reduce the risk of opportunistic infections indirectly by improving immune function, the core aspect is that it is a long-term management strategy rather than a definitive cure. Therefore, it's crucial to maintain realistic expectations regarding its efficacy.

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"Zidovudine therapy may result in the development of resistant strains."

"Zidovudine prevents the occurrence of opportunistic infections."

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